HM-MRI with Prostatectomy
Validated prostate tissue composition measurement using HM-MRI with reference standard quantitative histology results from whole mount prostatectomy
No significant difference in prostate tissue composition: stroma (p= 0.29), epithelium (p = 0.18) and lumen (p = 0.54) measured using HM-MRI and whole mount pathology.
Excellent correlation (overall = 0.89, stroma = 0.80, epithelium = 0.90, lumen = 0.86, p<0.05) between HM-MRIand whole mount pathology.
65 years old patient with Gleason 4+5 cancer in the right peripheral zone
Quantitative histology: stroma (green), epithelium (red) and lumen (blue) for ROIs.
HM-MRIaccurately measures tissue composition in PCaand normal TZ.